Aspiration Risk: Stopping Mounjaro 2.5 mg Before General Anesthesia

Patients on Mounjaro 2.5 mg may face a higher aspiration risk during general anesthesia because the medication slows gastric emptying, leaving food in the stomach longer than normal. To reduce this risk, most surgeons and anesthesiologists recommend stopping Mounjaro at least 1 week before surgery.
This pause helps ensure your stomach is empty on the day of the procedure and prevents dangerous complications such as vomiting under anesthesia. Always inform your surgical team that you use tirzepatide and follow their personalized instructions for medication hold times.

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