The Effect involving Zbxz23ir-21 NANO(nanomaterials) Supply Vector upon Apoptosis and also PTEN(phosphatase as well as tensin homolog removed about chromosome ten)/PI3K(Intracellular phosphatidylinositol kinase)/AKT(in connection with the actual A new as well as C kinase) in Children together with CHOLESTEATOMA inside Midsection Hearing.